Alexa Fluor® 488 anti-Lin28A Antibody
- 产品名称：
- Alexa Fluor® 488 anti-Lin28A Antibody
- 产品类别：
- 抗体
- 产品编号：
- 657807
- 产品应用：
- 657807
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2052 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Lin28A from E. coli
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Blue Laser (488 nm)
- Application Notes
This clone is specific for Lin28A does not?recognize Lin28B.
- RRID
- AB_2924623 (BioLegend Cat. No. 657807) AB_2924623 (BioLegend Cat. No. 657808)
- Structure
- 209 amino acids, predicted molecular weight of 28 kD with the characteristic of a cold shock domain (CSD) and two tandem Cys-Cys-His-Cys (CCHC)-type zinc-binding motifs (CCHCx2)
- Distribution
-
Cytoplasm and nucleus; localizes to cytoplasmic processing bodies and stress granules
- Function
- Development, self-renewal of stem cells, glucose metabolism and tumorigenesis; regulates Let-7 family miRNA, translation of mRNA
- Interaction
- EIF3S2, NCL and ZCCHC11/TUT4
- Cell Type
- Embryonic Stem Cells
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Chromatin Remodeling/Epigenetics, Immunology, Protein Synthesis, Signal Transduction, Stem Cells
- Antigen References
-
- Shyh-Chang N, et al. 2013. Cell Stem Cell. 12:395-406.
- Thornton JE, et al. 2012. Trends Cell Biol. 22:474-82.
- Huang Y. 2012. Wiley Interdiscip?Rev?RNA. 3:483-94.
- Cho J, et al. 2012. Cell. 151:765-777.
- Li N, et al. 2012. J?Biol Chem. 287:17386-17397.
- Zhu H, et al. 2011. Cell 147:81-94.
- Gene ID
- 79727 View all products for this Gene ID
- UniProt
- View information about Lin28A on UniProt.org
