PE/Cyanine7 anti-mouse Ly-49C/F/I/H Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1908	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Syrian Hamster

Immunogen

IL-2-activated killer cells (LAK) from C57BL/6 mice

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

Additional reported applications (for the relevant formats) include: induction of redirected lysis¹, and blocking² of the binding of H-2^d lymphoblasts to transfectants expressing Ly-49C, Ly-49F, and Ly-49I.

Additional Product Notes

BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.

Application References (PubMed link indicates BioLegend citation)

Corral L, et al. 1999. Hybridoma 18:359.
Hanke T, et al. 1999. Immunity 11:67.

RRID

AB_2728130 (BioLegend Cat. No. 108209) AB_2728131 (BioLegend Cat. No. 108210)

Disclaimer

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested for the University of California. The availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.

Antigen Details

Structure: Ly-49 family, 110 kD
Distribution: NK and NK-T cells, some CD8⁺ T cells
Function: NK cell activation or inhibition
Ligand/Receptor: MHC Class I Molecules
Cell Type: NK cells, NKT cells, T cells
Biology Area: Immunology, Innate Immunity
Molecular Family: CD Molecules
Antigen References: 1. Ryan JC, et al. 1997. Immunol. Rev. 155:79.
2. Mason LH, et al. 1997. J. Immunol. 159:4187.
3. Lanier LL. 1998. Ann. Rev. Immunol. 16:359.
4. Yokoyama W, et al. 1993. Ann. Rev. Immunol. 11:613.
Gene ID: 16634 View all products for this Gene ID
UniProt: View information about Ly-49C/F/I/H on UniProt.org

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