PE anti-mouse Ly-49C/F/I/H Antibody
- 产品名称:
- PE anti-mouse Ly-49C/F/I/H Antibody
- 产品类别:
- 抗体
- 产品编号:
- 108207
- 产品应用:
- 108207
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Syrian Hamster
- Immunogen
- IL-2-activated killer cells (LAK) from C57BL/6 mice
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: induction of redirected lysis1, and blocking2 of the binding of H-2d lymphoblasts to transfectants expressing Ly-49C, Ly-49F, and Ly-49I.
- Application References
(PubMed link indicates BioLegend citation) -
- Corral L, et al. 1999. Hybridoma 18:359.
- Hanke T, et al. 1999. Immunity 11:67.
- Product Citations
-
- Afolabi LO, et al. 2021. Front Immunol. 12:701671. PubMed
- RRID
- AB_2185816 (BioLegend Cat. No. 108207) AB_2185815 (BioLegend Cat. No. 108208)
- Disclaimer
This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested for the University of California. The availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.
- Structure
- Ly-49 family, 110 kD
- Distribution
-
NK and NK-T cells, some CD8+ T cells
- Function
- NK cell activation or inhibition
- Ligand/Receptor
- MHC Class I Molecules
- Cell Type
- NK cells, NKT cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Ryan JC, et al. 1997. Immunol. Rev. 155:79.
2. Mason LH, et al. 1997. J. Immunol. 159:4187.
3. Lanier LL. 1998. Ann. Rev. Immunol. 16:359.
4. Yokoyama W, et al. 1993. Ann. Rev. Immunol. 11:613.
- Gene ID
- 16634 View all products for this Gene ID
- UniProt
- View information about Ly-49C/F/I/H on UniProt.org