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FITC anti-human CD172a/b (SIRPα/β) Anti
产品名称:
FITC anti-human CD172a/b (SIRPα/β) Anti
产品类别:
抗体
产品编号:
337304
产品应用:
337304
[价格]
规格 价格 库存
100tests ¥ 2748 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications include: mAb 148 is specific for CD172a/b, and also stains CD172g transfected cells, but not T-lymphocytes

Application References

(PubMed link indicates BioLegend citation)
  1. Piccio L, et al. 2005. Blood 105:2421
  2. Dietrich J, et al. 2000. J. Immunol. 164:9
Product Citations
  1. Connor SM, et al. 2022. Front Cell Neurosci. 16:894601. PubMed
RRID
AB_2254620 (BioLegend Cat. No. 337304)

Antigen Details

Structure
Signal-regulatory-protein family, Ig superfamily
Distribution

Monocytes/macrophages, granulocytes, dendritic cells, neurons

Ligand/Receptor
CD172a binds CD47, CD172b interacts with DAP12
Cell Type
Dendritic cells, Granulocytes, Macrophages, Monocytes, Neurons
Biology Area
Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References

1. Kharitonenkov A, et al. 1997. Nature 386:181.
2. Tomasello E, et al. 2000. Eur. J. Immunol. 30:2147.
3. Seiffert M, et al. 2001. Blood 97:2741.
4. Timms JF, et al. 1998. Mol. Cell Biol. 18:3838.
5. Barclay AN and MH. Brown. 2006. Nat. Rev.Immnuol. 6:457

Gene ID
10326 View all products for this Gene ID 140885 View all products for this Gene ID
UniProt
View information about CD172alpha/beta on UniProt.org

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