Purified anti-rat CD38 Antibody
- 产品名称:
- Purified anti-rat CD38 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 250502
- 产品应用:
- 250502
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified
WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. For immunohistochemistry staining on frozen tissue sections, a concentration range of 2.5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemistry1 and Western blotting1.
- Application References
(PubMed link indicates BioLegend citation) -
- March S, et al. 2007. Am. J. Pathol. 170:176. (IHC, WB)
- Product Citations
-
- Ardiana M, et al. 2022. F1000Res. 10:917. PubMed
- Boslett J, et al. 2018. Am J Physiol Cell Physiol. 314:C297. PubMed
- RRID
- AB_2562587 (BioLegend Cat. No. 250502)
- Structure
- CD38 is a 45 kD type II transmembrane protein.
- Distribution
-
Early hematopoietic precursors and leukocytes, astrocytes, hepatic stellate cells, and epithelial cells; upregulated upon activation.
- Function
- CD38 catalyzes the production of cyclic APD ribose, which is important in Ca2+ release. CD38 induces production of proinflammatory cytokines and proliferation.
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- Astrocytes, B cells, Dendritic cells, Epithelial cells, Leukocytes
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, MHC Antigens
- Antigen References
-
1. Ota H, et al. 2012. Life Sci. 90:206.
2. Masuda W, et al. 2011. Arch. Biochem. Biophys. 2:131.
3. Khoo KM, et al. 1998. Biochem. Mol. Biol. Int. 44:841.
4. Prasad GS, et al. 1996. Nat. Struct. Biol. 3:957.
- Gene ID
- 25668 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org