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Purified anti-rat CD38 Antibody
产品名称:
Purified anti-rat CD38 Antibody
产品类别:
抗体
产品编号:
250502
产品应用:
250502
[价格]
规格 价格 库存
100µg ¥ 2328 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. For immunohistochemistry staining on frozen tissue sections, a concentration range of 2.5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemistry1 and Western blotting1.

Application References

(PubMed link indicates BioLegend citation)
  1. March S, et al. 2007. Am. J. Pathol. 170:176. (IHC, WB)
Product Citations
  1. Ardiana M, et al. 2022. F1000Res. 10:917. PubMed
  2. Boslett J, et al. 2018. Am J Physiol Cell Physiol. 314:C297. PubMed
RRID
AB_2562587 (BioLegend Cat. No. 250502)

Antigen Details

Structure
CD38 is a 45 kD type II transmembrane protein.
Distribution

Early hematopoietic precursors and leukocytes, astrocytes, hepatic stellate cells, and epithelial cells; upregulated upon activation.

Function
CD38 catalyzes the production of cyclic APD ribose, which is important in Ca2+ release. CD38 induces production of proinflammatory cytokines and proliferation.
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
Astrocytes, B cells, Dendritic cells, Epithelial cells, Leukocytes
Biology Area
Immunology
Molecular Family
Adhesion Molecules, MHC Antigens
Antigen References

1. Ota H, et al. 2012. Life Sci. 90:206.
2. Masuda W, et al. 2011. Arch. Biochem. Biophys. 2:131.
3. Khoo KM, et al. 1998. Biochem. Mol. Biol. Int. 44:841.
4. Prasad GS, et al. 1996. Nat. Struct. Biol. 3:957.

Gene ID
25668 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org

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