Purified anti-AIP1 Antibody
- 产品名称：
- Purified anti-AIP1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 645601
- 产品应用：
- 645601
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Full length recombinant protein expressed in E Coli
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5 - 1 ?g per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Li J, et al. 2007. Nature Cell Biology 9:276
- RRID
- AB_2063814 (BioLegend Cat. No. 645601)
- Structure
- A protein of 67-kd WD-repeat protein. It contains as many as 10 WD repeats which is characterized by homologous sequence of around 40 amino acids with Trip-Asp(WD) at the carboxyl ends.
- Function
- Enhance actin filament disassembly in the presence of actin-depolymerizing factor cofilin.
- Interaction
- AIP1 binds cofilin/actin depolymerization factor.
- Ligand/Receptor
- Caspase-11 interacts physically with AIP1 to promote cofilin-mediated actin depolymerization.
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure
- Antigen References
-
1. Voegtli WC, et al. 2003 J. Biol. Chem. 278:34373
2. Mohri K, et al. 2004. J. Biol. Chem. 279:31697
- Gene ID
- 22388 View all products for this Gene ID
- UniProt
- View information about AIP1 on UniProt.org
