PE anti-human CCX-CKR (CCRL1) Antibody
- 产品名称：
- PE anti-human CCX-CKR (CCRL1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 362103
- 产品应用：
- 362103
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length CCX-CKR cDNA
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications for the relevant formats include: immunoprecipitation of CCX-CKR from cell lysates1, induction of CCX-CKR internalization1?and immunofluorescence1. 13E11 recognizes an epitope located within the first 14 amino acids of CCX-CKR.
- Application References
(PubMed link indicates BioLegend citation) -
- Takatsuka, S. et al. 2011. J. Pharmacol. Toxicol. Methods. 63:250. (IF, IP, Agonist)
- RRID
- AB_2563934 (BioLegend Cat. No. 362103) AB_2563935 (BioLegend Cat. No. 362104)
- Structure
- G-protein-coupled seven transmembrane receptor, 40 kD.
- Distribution
-
Stromal cells of skin-draining lymph nodes, thymic epithelial cells, immature DCs.
- Function
- C-C type chemokine scavenger and decoy receptor, reduces chemokine availability by sequestering them inside the cell.
- Interaction
- β-arrestin.
- Ligand/Receptor
- CCL2, CCL8, CCL13, CCL19, CCL21, and CCL25.
- Cell Type
- Dendritic cells, Epithelial cells
- Biology Area
- Immunology
- Molecular Family
- Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Watts AO, et al. 2013. J. Biol. Chem. 288:7169.?
2. Comerford I, et al. 2010. Blood. 116:4130.
?
- Gene ID
- 51554 View all products for this Gene ID
- UniProt
- View information about CCX-CKR on UniProt.org
