Purified anti-human PlGF Antibody
- 产品名称：
- Purified anti-human PlGF Antibody
- 产品类别：
- 抗体
- 产品编号：
- 534802
- 产品应用：
- 534802
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ELISA-C - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by ELISA assay. For ELISA Capture applications, a concentration range of 1.0 - 4.0 ?g/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
The purified 13C8 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated 24G3 antibody (Cat. No. 534904) as the detecting antibody.
- RRID
- AB_2894608 (BioLegend Cat. No. 534802)
- Structure
- Homodimer
- Distribution
-
Vascular endothelial cells, smooth muscle cells, keratinocytes, hematopoitic cells, retinal pigment epithelial cells, tumor cells, and cerebellar stroma cells.
- Function
- PlGF is an angiogenic factor and induces proliferation and migration of endothelial cells. It stimulates endothelial cells and synergistically amplifies the action of VEGF. Soluble VEGFR1 (sFLT1) can regulate the accessibility of PlGF.
- Interaction
- Endothelial cells, Macrophages, and trophoblats
- Ligand/Receptor
- VEGFR1 (FLT-1) and neuropilin 1 (Nrp1)
- Cell Type
- Endothelial cells, Epithelial cells, Hematopoietic stem and progenitors
- Antigen References
-
- Maglione D, et al. 1991. Proc Natl Acad Sci USA. 88:9267.
- Carmeliet P, et al. 2001. Nat Med. 7:575.
- Casalou C, et al. 2007. Leukemia. 21:1590.
- Marcellini M, et al. 2006. Am J Pathol. 169:643.
- Yao J, et al. 2011. Proc Natl Acad Sci USA. 108:11590.
- Cai J, et al. 2011. PLoS One. 6:e18076.
- Sibiude J, et al. 2012. PLoS One. 7:e50208.
- Snuderl M, et al. 2013. Cell. 152:1065.
- Gene ID
- 5228 View all products for this Gene ID
- UniProt
- View information about PlGF on UniProt.org
