Purified anti-mouse CD317 (BST2, PDCA-1) Antibody
- 产品名称：
- Purified anti-mouse CD317 (BST2, PDCA-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 127102
- 产品应用：
- 127102
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse plasmacytoid dendritic cells (DCs)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Blasius AL, et al. 2006. J. Immunol. 177:3260
- Cocka LJ, et al. 2012. PLoS Pathog. 8:e1002931. PubMed.
- Product Citations
-
- Cocka L, Bates P 2012. PLoS One. 8:e1002931. PubMed
- Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
- Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
- Olety B, et al. 2021. Sci Adv. 7:eabj7398. PubMed
- RRID
- AB_1953279 (BioLegend Cat. No. 127102)
- Structure
- Type II transmembrane glycoprotein with a molecular mass of 29-33 kD.
- Distribution
- Expressed on type I IFN-producing cells, plasmacytoid dendritic cells, and neoplastic B cells, such as multiple myeloma.
- Function
- Recently identified as antiviral protein that blocks the release of nascent retrovirus or other particles from infected cells.
- Cell Type
- Dendritic cells, B cells
- Biology Area
- Immunology, Innate Immunity, Costimulatory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Douglas JL. et al. 2009. J Virol. 83(16):7931
2. Cao W et al. 2009. J. Exp. Med. 206(7):1603
3. Neil SJ. et al. 2008. Nature 451:425
- Gene ID
- 69550 View all products for this Gene ID
- UniProt
- View information about CD317 on UniProt.org
