PE anti-mouse CD317 (BST2, PDCA-1) Antibody
- 产品名称：
- PE anti-mouse CD317 (BST2, PDCA-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 127103
- 产品应用：
- 127103
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse plasmacytoid dendritic cells (DCs)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Blasius AL, et al. 2006. J. Immunol. 177:3260
- Kojima K, et al. 2011. Am J Respair Crit Care Med. 184:328. PubMed.
- Product Citations
-
- Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
- Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
- Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
- Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
- Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
- Kojima K, et al. 2011. Am J Respir Crit Care Med. 184:328. PubMed
- Lorenz G, et al. 2022. J Innate Immun. :1. PubMed
- RRID
- AB_1953282 (BioLegend Cat. No. 127103) AB_1953283 (BioLegend Cat. No. 127104)
- Structure
- Type II transmembrane glycoprotein with a molecular mass of 29-33 kD.
- Distribution
-
Expressed on type I IFN-producing cells, plasmacytoid dendritic cells, and neoplastic B cells, such as multiple myeloma.
- Function
- Recently identified as antiviral protein that blocks the release of nascent retrovirus or other particles from infected cells.
- Cell Type
- Dendritic cells, B cells
- Biology Area
- Immunology, Innate Immunity, Costimulatory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Douglas JL, et al. 2009. J Virol. 83(16):7931
2. Cao W, et al. 2009. J. Exp. Med. 206(7):1603
3. Neil SJ, et al. 2008. Nature 451:425
- Gene ID
- 69550 View all products for this Gene ID
- UniProt
- View information about CD317 on UniProt.org
