Alexa Fluor® 647 anti-mouse CD317 (BST2, PDCA-
- 产品名称：
- Alexa Fluor® 647 anti-mouse CD317 (BST2, PDCA-
- 产品类别：
- 抗体
- 产品编号：
- 127105
- 产品应用：
- 127105
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse plasmacytoid dendritic cells (DCs)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Blasius AL, et al. 2006. J. Immunol. 177:3260.
- Product Citations
-
- Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
- Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
- Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
- RRID
- AB_2228222 (BioLegend Cat. No. 127105) AB_2067120 (BioLegend Cat. No. 127106)
- Structure
- Type II transmembrane glycoprotein with a molecular mass of 29-33 kD.
- Distribution
- Expressed on type I IFN-producing cells, plasmacytoid dendritic cells, and neoplastic B cells, such as multiple myeloma.
- Function
- Recently identified as antiviral protein that blocks the release of nascent retrovirus or other particles from infected cells.
- Cell Type
- Dendritic cells, B cells
- Biology Area
- Immunology, Innate Immunity, Costimulatory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Douglas JL, et al. 2009. J Virol. 83:7931.
2. Cao W, et al. 2009. J. Exp. Med. 206:1603.
3. Neil SJ, et al. 2008. Nature 451:425.
- Gene ID
- 69550 View all products for this Gene ID
- UniProt
- View information about CD317 on UniProt.org
