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首页 > 抗体蛋白 > 抗体
Purified anti-LRP1 (CD91) Antibody
产品名称：
Purified anti-LRP1 (CD91) Antibody
产品类别：
抗体
产品编号：
858701
产品应用：
858701
[价格]
规格 价格 库存
25µg ￥ 1272 1

产品详情

Product Details

Verified Reactivity
Human, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody recognizes the beta chain of LRP1.

Application References

(PubMed link indicates BioLegend citation)
  1. Spoelgen R, et al. 2009. Neuroscience. 158(4):1460 (WB)
  2. Lleó A, et al. 2005. J Biol Chem. 280(29):27303 (WB, ICC)
  3. Campana WM, et al. 2006. J Neurosci. 26(43):11197 (WB, IHC)
  4. Nieves EC and Manchanda N. 2010. J Biol Chem. 285(17):12595 (IP)
RRID
AB_2801223 (BioLegend Cat. No. 858701) AB_2801224 (BioLegend Cat. No. 858702)

Antigen Details

Structure
The beta chain of LRP1 is a 601 amino acid protein with a molecular mass of 85 kD.
Distribution

Tissue Distribution: brain, lung, adipose tissue, and reproductive system.
Cellular Distribution: plasma membrane, nucleus, cytosol, lysosome, and endosome.

Function
Receptor-mediated endocytosis; lipoprotein metabolism
Interaction
SHC1, GULP1, DAB1, LRPAP1, NPXY
Ligand/Receptor
Receptor for APOE4/APOE, Alpha-2-macroglobulin, Pseudomonas aeruginosa exotoxin A
Cell Type
Microglia, Oligodendrocytes
Biology Area
Cell Motility/Cytoskeleton/Structure, Protein Trafficking and Clearance, Signal Transduction
Molecular Family
Apolipoproteins, Tumor Suppressors
Antigen References
  1. Actis Dato V and Chiabrando GA. 2018. Int J Mol Sci. E1780
  2. Storck SE and Pietrzik CU, 2017. Pharm Res. 34(12):2637
  3. Holtzman DM, et al. 2012, Cold Spring Harb Perspect Med. 2(3):a006312
Gene ID
4035 View all products for this Gene ID 299858 View all products for this Gene ID
UniProt
View information about LRP1 on UniProt.org

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