PE anti-human CD226 (DNAM-1) Antibody
- 产品名称：
- PE anti-human CD226 (DNAM-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 338305
- 产品应用：
- 338305
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1464 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications include: block NK cell-mediated lysis.
- Application References
(PubMed link indicates BioLegend citation) -
- Fuchs A, et al. 2004. J. Immunol. 172:3994.
- Product Citations
-
- Weulersse M, et al. 2020. Immunity. 53(4):824-839.e10. PubMed
- Fuhrman C, et al. 2015. J Immunol. 195: 145 - 155. PubMed
- Wragg KM, et al. 2020. Cell Reports. 31(11):107773. PubMed
- Kobayashi Y, et al. 2020. Int J Oncol. 999:56. PubMed
- Dean JW, et al. 2020. J Autoimmun. 108:102417. PubMed
- Huang RS, et al. 2021. Curr Protoc. 1:e246. PubMed
- Gilchrist JJ, et al. 2022. Nat Commun. 13:4073. PubMed
- Damele L, et al. 2021. Cancers (Basel). 13:. PubMed
- Rosskopf S, et al. 2018. Oncotarget. 9:17608. PubMed
- RRID
- AB_2259834 (BioLegend Cat. No. 338305) AB_2275498 (BioLegend Cat. No. 338306)
- Structure
- Ig domain containing adhesion molecule
- Distribution
-
Peripheral blood T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells
- Function
- Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell
- Interaction
- Interacts with LFA-1.
- Ligand/Receptor
- PVR (CD155) and Nectin-2 (CD112)
- Cell Type
- B cells, Macrophages, Megakaryocytes, Monocytes, NK cells, Platelets, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Shibuya A et al. 1996. Immunity 4:573.
2. Tahara-Hanaoka S et al. 2004. Int. Immunol. 16:533.
3. Pende D et al. 2005. Mol. Immunol. 42:463.
- Gene ID
- 10666 View all products for this Gene ID
- UniProt
- View information about CD226 on UniProt.org
