FITC anti-human CD226 (DNAM-1) Antibody
- 产品名称：
- FITC anti-human CD226 (DNAM-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 338303
- 产品应用：
- 338303
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1212 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications include: block NK cell-mediated lysis.
- Application References
(PubMed link indicates BioLegend citation) -
- Fuchs A, et al. 2004. J. Immunol. 172:3994.
- Product Citations
-
- Kritikou J, et al. 2016. Sci Rep. 6:30636. PubMed
- Guiliani E, et al. 2017. Immunol Lett. 10.1016/j.imlet.2017.08.014. PubMed
- Bertulli C, et al. 2020. Int J Mol Sci. 21:. PubMed
- Hood SP, et al. 2020. Elife. 9:00. PubMed
- Williams L, et al. 2016. J Virol. 90: 947 - 958. PubMed
- RRID
- AB_1279145 (BioLegend Cat. No. 338303) AB_2228763 (BioLegend Cat. No. 338304)
- Structure
- Ig domain containing adhesion molecule
- Distribution
-
Peripheral blood T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells
- Function
- Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell
- Interaction
- Interacts with LFA-1.
- Ligand/Receptor
- PVR (CD155) and Nectin-2 (CD112)
- Cell Type
- B cells, Macrophages, Megakaryocytes, Monocytes, NK cells, Platelets, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Shibuya A et al. 1996. Immunity 4:573.
2. Tahara-Hanaoka S et al. 2004. Int. Immunol. 16:533.
3. Pende D et al. 2005. Mol. Immunol. 42:463.
- Gene ID
- 10666 View all products for this Gene ID
- UniProt
- View information about CD226 on UniProt.org
