上海细胞库
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
| 规格 | 价格 | 库存 |
|---|---|---|
| 50ul | ￥ 1200 | 8 |
| 100ul | ￥ 1900 | 7 |
| 200ul | ￥ 2900 | 3 |
| 品编号 | Ys-2145R |
| 英文名称 | Hrasls3 |
| 中文名称 | HRAS样抑制因子3抗体 |
| 别 名 | H rev 107 protein homolog; HRAS like suppressor 3; HREV107 3; HREV107; Renal carcinoma antigen NY REN 65; Adipose specific phospholipase A2; Group XVI phospholipase A2; HREV107; HRSL3_MOUSE; AdPLA; HRSL3; HRASLS3; HREV107-1; HREV107-3; H-REV107-1. |
| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 18kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from the middle of mouse Hrasls3: 8-100/162 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 | HRASLS3 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue and also has a weak lysophospholipase activity. It is a tumor suppressor that may be involved in interferon-dependent cell death. Function: Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N-and O-acylation activity is hardly detectable. Also has weak lysophospholipase activity. Subunit: Interacts with PPP2R1A; this interaction might decrease PP2A activity. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, perinuclear region. Tissue Specificity: Ubiquitously expressed in normal tissues but down-regulated in primary carcinomas or in many cell lines derived from tumors. Highly expressed in white adipose tissue and in adipocytes. Expressed at lower levels in brown adipose tissue. Similarity: Belongs to the H-rev107 family. |
