首页 > 抗体蛋白 > 抗体
醛缩酶A抗体
产品名称:
醛缩酶A抗体
英文名称:
Aldolase A
产品类别:
抗体
产品编号:
Ys-2406R
产品应用:
WB ELISA IHC-P IHC-F Flow-Cyt IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 6
200ul ¥ 2900 4

产品详情

 

产品编号 Ys-2406R
英文名称 Aldolase A
中文名称 醛缩酶A抗体
别    名 ALDA; Aldo1; ALDOA; ALDOA_HUMAN; Aldolase 1; Aldolase A; Aldolase A fructose bisphosphatase; Aldolase A fructose bisphosphate; FRUCTOALDOLASE A; Fructose 1 6 bisphosphate triosephosphate lyase; Fructose bisphosphate aldolase A; Fructose bisphosphate aldolase; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE A; Fructose-bisphosphate aldolase A; Fructose-bisphosphate aldolase A Muscle-type; GSD12; Lung cancer antigen NY LU 1; Lung cancer antigen NY-LU-1; MGC10942; MGC17716; MGC17767; Muscle type aldolase; Muscle-type aldolase; RNALDOG5.  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Horse, Rabbit, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg /test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Aldolase A: 261-364/364 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Research areas:Cancer //Cancer Metabolism //Metabolic signaling pathway <
Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Cellular localization:Cytoplasmic
Tissue Specificity:adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue.

Function:
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.

Subunit:
Homotetramer. Interacts with SNX9 and WAS.

DISEASE:
Glycogen storage disease 12 (GSD12) [MIM:611881]: A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class I fructose-bisphosphate aldolase family.

SWISS:
P04075

联系我们

TEL:021-34661275  点击拨打热线