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G蛋白偶联受体LGR7蛋白抗体
产品名称:
G蛋白偶联受体LGR7蛋白抗体
英文名称:
GPCR LGR7
产品类别:
抗体
产品编号:
Ys-15368R
产品应用:
WB ELISA IHC-P IHC-F ICC IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 6
200ul ¥ 2900 3

产品详情

 


产品编号 Ys-15368R
英文名称 GPCR LGR7
中文名称 G蛋白偶联受体LGR7蛋白抗体
别    名 Gm1018; Leucine rich repeat containing G protein coupled receptor 7;LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; Relaxin/insulin like family peptide receptor 1; RXFP 1; RXFP1; RXFP1; RXFP1_HUMAN; RXFPR1.  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Cow, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 87kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPCR LGR7: 301-400/757 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Function:
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.

Similarity:
Belongs to the G-protein coupled receptor 1 family.
Contains 1 LDL-receptor class A domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.

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