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Notch配体Jagged 2蛋白抗体
产品名称:
Notch配体Jagged 2蛋白抗体
英文名称:
Jagged 2
产品类别:
抗体
产品编号:
Ys-4244R
产品应用:
WB ELISA IHC-P
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 6
200ul ¥ 2900 5

产品详情

 

产品编号 Ys-4244R
英文名称 Jagged 2
中文名称 Notch配体Jagged 2蛋白抗体
别    名 D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 134kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Jagged 2: 201-300/1238 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.

Similarity:
Contains 1 DSL domain.
Contains 16 EGF-like domains.
Contains 1 VWFC domain.

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