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肿瘤转移抑制蛋白1抗体
产品名称:
肿瘤转移抑制蛋白1抗体
英文名称:
CD82
产品类别:
抗体
产品编号:
Ys-1470R
产品应用:
ELISA IHC-P IHC-F ICC IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 5
200ul ¥ 2900 3

产品详情

 

产品编号 Ys-1470R
英文名称 CD82
中文名称 肿瘤转移抑制蛋白1抗体
别    名 4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KAI1; Kangai 1; Kangai1; Metastasis suppressor Kangai 1; Metastasis suppressor Kangai1; R2 leukocyte antigen; CD82_HUMAN.   
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 29kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD82: 165-267/267 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.

Subunit:
Interacts directly with IGSF8.

Subcellular Location:
Membrane.

Tissue Specificity:
Lymphoid specific.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

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