规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 5 |
100ul | ¥ 1900 | 2 |
200ul | ¥ 2900 | 3 |
产品编号 | Ys-12518R |
英文名称 | Argonaute 4 |
中文名称 | 真核翻译起始因子2C4抗体 |
别 名 | eIF2C4; 5730550L01Rik; Ago 4; Ago4; AGO4_HUMAN; Argonaute4; EIF 2C 4; eIF-2C 4; eIF2C 4; Eif2c4; eukaryotic translation initiation factor 2C 4; eukaryotic translation initiation factor 2C; hAgo4; KIAA1567; Piwi/Argonaute family protein meIF2C4; Protein argonaute-4. |
研究领域 | 细胞生物 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 97kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Argonaute 4/eIF2C4: 401-500/861 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1. [provided by RefSeq, Jul 2008] Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Subunit: Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Subcellular Location: Cytoplasm. Similarity: Belongs to the argonaute family. Ago subfamily. Contains 1 PAZ domain. Contains 1 Piwi domain.Cellular localization. |