规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 5 |
100ul | ¥ 1900 | 3 |
200ul | ¥ 2900 | 2 |
产品编号 | Ys-21862R |
英文名称 | SSTR4 |
中文名称 | 生长抑素受体4抗体 |
别 名 | somatostatin receptor 4; Smstr4; Somatostatin receptor type 4; SS 4R; SS4R; SST R4; SSTR 4; SSTR4; SSR4_HUMAN. |
研究领域 | 肿瘤 细胞凋亡 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, (predicted: Rat, ) |
产品应用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 42kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse SSTR4 : 141-240/385 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. Its function is to inhibit the release of many hormones and other secretory proteins. Function: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals. Similarity: Belongs to the G-protein coupled receptor 1 family. |