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骨骼肌快/慢肌肌钙蛋白I抗体
产品名称:
骨骼肌快/慢肌肌钙蛋白I抗体
英文名称:
Troponin I fast + slow skeletal muscle
产品类别:
抗体
产品编号:
Ys-10617R
产品应用:
WB ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 5
200ul ¥ 2900 2

产品详情

 

产品编号 Ys-10617R
英文名称 Troponin I fast + slow skeletal muscle
中文名称 骨骼肌快/慢肌肌钙蛋白I抗体
别    名 AMCD2B; DA2B; DKFZp451O223; Fast twitch skeletal muscle troponin I; FSSV; fsTnI; OTTHUMP00000014141; OTTHUMP00000014142; OTTHUMP00000014143; OTTHUMP00000033877; OTTHUMP00000033909; OTTHUMP00000033910; SSTNI; TNN1; Troponin I fast twitch 2; Troponin I type 1 (skeletal, slow); Troponin I type 2 (skeletal, fast); Troponin I, fast skeletal muscle; Troponin I, fast twitch isoform; Troponin I, fast twitch skeletal muscle isoform; Troponin I, skeletal, fast; Troponin I, slow skeletal muscle; Troponin I, slow twitch isoform; TNNI1_HUMAN; TNNI2_HUMAN.  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Chicken, Pig, Cow, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 33kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNNI1+TNNI2 : 51-150/182 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.

Function:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Subunit:
Binds to actin and tropomyosin.

DISEASE:
Arthrogryposis, distal, 2B (DA2B) [MIM:601680]: A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the troponin I family.

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