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畸胎瘤衍化生长因子抗体(N端)
产品名称:
畸胎瘤衍化生长因子抗体(N端)
英文名称:
CRIPTO
产品类别:
抗体
产品编号:
Ys-1566R
产品应用:
ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 8
100ul ¥ 1900 5
200ul ¥ 2900 3

产品详情

产品编号 Ys-1566R
英文名称 CRIPTO
中文名称 畸胎瘤衍化生长因子抗体(N端)
别    名 CRIPTO; CRIPT; CR; CRGF; Cripto 1; Cripto-1; Cripto 1 growth factor; Cripto-1 growth factor; Cripto1; Cripto1 growth factor; Epidermal growth factor like cripto protein CR1; Epidermal growth factor-like cripto protein CR1; TDGF 1; TDGF-1; TDGF1; Teratocarcinoma derived growth factor 1; Teratocarcinoma-derived growth factor 1; teratocarcinoma-derived growth factor 1 isoform 1 precursor; TDGF1_HUMAN.  
  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 13kDa
细胞定位 细胞膜 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TDGF1: 31-150/188 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

Function:
Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

Subunit:
Interacts with the activin type-1 receptor ACVR1B.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung.

Similarity:
Contains 1 EGF-like domain.

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