规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 8 |
100ul | ¥ 1900 | 6 |
200ul | ¥ 2900 | 3 |
产品编号 | Ys-1880R |
英文名称 | PTGEs/Prostaglandin E Synthase |
中文名称 | 前列腺素E合成酶抗体 |
别 名 | Glutathione S transferase 1 like 1; MGC10317; MGST IV; MGST1 L1; MGST1 like 1; MGST1-L1; MGST1L1; MGSTIV; Microsomal glutathione S transferase 1 like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; Microsomal prostaglandin E synthase 1; mPGES 1; MPGES; mPGES-1; p53 induced apoptosis protein 12; p53 induced gene 12; p53 induced gene 12 protein; p53-induced gene 12 protein; PGES; PIG 12; PIG12; PP 102; PP 1294; PP102; PP1294; Prostaglandin E synthase; PTGES; PTGES_HUMAN; TP53I12; Tumor protein p53 inducible protein 12. |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, (predicted: Mouse, Rat, Guinea Pig, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 17kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PTGEs: 85-152/152 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. Function: Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Subunit: Homotrimer. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the MAPEG family. |