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基质金属蛋白酶-15抗体
产品名称:
基质金属蛋白酶-15抗体
英文名称:
MMP15
产品类别:
抗体
产品编号:
Ys-1855R
产品应用:
WB ELISA
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
200ul ¥ 2900 2
100ul ¥ 1900 1

产品详情

 

产品编号 Ys-1855R
英文名称 MMP15
中文名称 基质金属蛋白酶-15抗体
别    名 Matrix metalloproteinase-15; MMP 15; MMP-15; MMP15; Matrix metallopeptidase 15 membrane inserted; Matrix metalloproteinase 15 ; Membrane type 2 Matrix Metalloproteinase; Membrane type matrix metalloproteinase 2; MT MMP 2; MT2 MMP; MT2MMP; MTMMP 2; MTMMP2; SMCP 2; SMCP2; MMP15_HUMAN.    
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 61/76kDa
细胞定位 细胞膜 细胞外基质 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MMP15: 501-600/669 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008].

Function:
Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.

Subcellular Location:
Membrane; Single-pass type I membrane protein; Extracellular side.

Tissue Specificity:
Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity).

Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.

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