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肝肠钙粘连蛋白抗体
产品名称:
肝肠钙粘连蛋白抗体
英文名称:
LI Cadherin
产品类别:
抗体
产品编号:
Ys-1617R
产品应用:
WB ELISA IHC-P
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
100ul ¥ 1200 8
200ul ¥ 2900 6
50ul ¥ 1200 3

产品详情

 

产品编号 Ys-1617R
英文名称 LI Cadherin
中文名称 肝肠钙粘连蛋白抗体
别    名 BILL-cadherin; LI-cadherin; CAD17_HUMAN; Cadherin 16; Cadherin 16, formerly; Cadherin 17; cadherin 17, LI cadherin (liver-intestine); cadherin, liver-intestine; Cadherin-17; CDH16; CDH16, formerly; Cdh17; FLJ26931; Formerly Cadherin 16; Formerly CDH16; HPT 1; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT 1; Intestinal peptide-associated transporter HPT-1; LI-cadherin; Liver Cadherin; liver intestine cadherin; Liver-intestine cadherin.  
研究领域 免疫学  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 90kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LI-cadherin: 101-200/832 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Potential).

Tissue Specificity:
Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.

Similarity:
Contains 7 cadherin domains.

SWISS:
Q12864

Gene ID:
1015

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