缓激肽B2受体抗体-上海雅吉生物科技有限公司

规格	价格	库存
50ul	￥ 1200	8
100ul	￥ 1900	6
200ul	￥ 2900	3

产品编号	Ys-2422R
英文名称	BDKRB2
中文名称	缓激肽B2受体抗体
别名	B2; B2 bradykinin receptor; B2BKR; B2BRA; B2R; BDKR B2; BDKRB 2; Bdkrb2; BK 2; BK 2 receptor; BK R2; BK2; BK2 receptor; BK2R; BKR 2; BKR2; BR B2; Bradykinin receptor b2; Bradykinin receptor beta 2; BRB 2; BRB2; DKFZp686O088; Kinin B2 Bradykinin receptor beta 2; B2R.

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

Mouse, Rat, (predicted: Human, )

产品应用

ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

理论分子量

43kDa

细胞定位

细胞膜

性状

Liquid

浓度

1mg/ml

免疫原

KLH conjugated synthetic peptide derived from human Bdkrb2: 51-150/391

亚型

IgG

纯化方法

affinity purified by Protein A

缓冲液

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMed

产品介绍

Bradykinin increases vascular permeability, dilates blood vessels, contracts non-vascular smooth muscle, and causes pain. This product detects a receptor for bradykinin. The receptor is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung,prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.

Function:
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Subunit:
Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.

SWISS:
P30411

缓激肽B2受体目前主要在糖尿病肾病的发生、发展中起着重要作用。

产品图片

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Bdkrb2/B2R Polyclonal Antibody, Unconjugated(2422R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

上海细胞库

原代细胞

细胞培养

细胞服务

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生化试剂盒

PCR试剂盒

抗体蛋白

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