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末端脱氧核苷酸转移酶抗体
产品名称:
末端脱氧核苷酸转移酶抗体
英文名称:
DNTT
产品类别:
抗体
产品编号:
Ys-2938R
产品应用:
ELISA IHC-P IHC-F Flow-Cyt IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 5
200ul ¥ 2900 4

产品详情

 

产品编号 Ys-2938R
英文名称 DNTT
中文名称 末端脱氧核苷酸转移酶抗体
别    名 Deoxynucleotidyltransferase terminal; DNA nucleotidylexotransferase; TdT; Nucleosidetriphosphate DNA deoxynucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase; TDT_HUMAN.    
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, Dog, Horse, Rabbit, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TdT/DNTT: 351-450/509 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Subunit:
Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the DNA polymerase type-X family.
Contains 1 BRCT domain.

SWISS:
P04053

Gene ID:
1791

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