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瞬时受体电位通道1抗体
产品名称:
瞬时受体电位通道1抗体
英文名称:
TRPC1
产品类别:
抗体
产品编号:
YS-10404R
产品应用:
ELISA Flow-Cyt ICC
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 7
100ul ¥ 1900 6
200ul ¥ 2900 3

产品详情

 

产品编号 YS-10404R
英文名称 TRPC1
中文名称 瞬时受体电位通道1抗体
别    名 TRPC1_HUMAN; Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1; TRP 1; TRP 1 protein; TRP1; TRP1 protein; . HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Transient receptor potential cation channel subfamily C member 1; Transient receptor potential channel 1; Trp related protein 1; TRPC1; Trpc1 transient receptor potential cation channel subfamily C member 1.  

 

抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 ELISA=1:5000-10000 Flow-Cyt=3ug/test ICC=1:100-500 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 87kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRPC1: 710-750/793 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

Function:
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Subunit:
Interacts with TRPC4AP. Homotetramer and heterotetramer with TRPC4 and/or TRPC5. Interacts with TRPC3, TRPC4 and TRPC5. Interacts with ITPR3. Interacts with MX1 and RNF24. Interacts with FKBP4.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Seems to be ubiquitous.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
Contains 4 ANK repeats.

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