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钾电压阀门通道混合器相关亚家族成员7抗体
产品名称:
钾电压阀门通道混合器相关亚家族成员7抗体
英文名称:
KCNA7
产品类别:
抗体
产品编号:
Ys-3656R
产品应用:
WB ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
12个月
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 8
100ul ¥ 1900 6
200ul ¥ 2900 3

产品详情

 

产品编号 Ys-3656R
英文名称 KCNA7
中文名称 钾电压阀门通道混合器相关亚家族成员7抗体
别    名 HAK 6; HAK6; KCNA 7; KV1.7; Potassium voltage gated channel shaker related subfamily member 7; Potassium voltage gated channel subfamily A member 7; Voltage dependent potassium channel Kv1.7; Voltage gated potassium channel KCNA7; Voltage gated potassium channel subunit Kv1.7.  
研究领域 免疫学  神经生物学  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Rabbit, )
产品应用 WB=1:500-2000 ELISA=1:2000-5000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 50kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNA7: 251-350/456 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders. [provided by RefSeq, Jul 2008]

Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity).

Subunit:
Heterotetramer of potassium channel proteins.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly expressed in skeletal muscle, heart and kidney.

Similarity:
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.7/KCNA7 sub-subfamily.

SWISS:
Q96RP8

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