规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 8 |
100ul | ¥ 1900 | 5 |
200ul | ¥ 2900 | 3 |
产品编号 | Ys-7723R |
英文名称 | REC8 |
中文名称 | 减数分裂重组蛋白家族REC8抗体 |
别 名 | Cohesin Rec8p; Meiotic recombination protein REC8 homolog; Meiotic recombination protein REC8-like 1; rec8; REC8 homolog (yeast); REC8_HUMAN; REC8L; Rec8L1; Rec8p. |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, (predicted: Dog, Pig, Horse, Rabbit, Guinea Pig, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/Test IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 60kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human REC8: 22-120/547 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. Function: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity). Subunit: Interacts (phosphorylated and unphosphorylated form) with SMC3. Interacts with SYCP3. Interacts (phosphorylated and unphosphorylated form) with SMC1B. Does not interact with SMC1A. Interacts with RAD51. Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Expressed in testis and thymus. Similarity: Belongs to the rad21 family. SWISS: O95072 Gene ID: 9985 |