规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 8 |
100ul | ¥ 1900 | 6 |
200ul | ¥ 2900 | 5 |
产品编号 | Ys-0507R |
英文名称 | TBX2 |
中文名称 | 血栓素B2(一种新发现的抑癌基因)抗体 |
别 名 | T-box2; T-box Protein 2; T-box transcription factor TBX2; T-box protein 2; FLJ10169; HGNC: 11597; T box 2; T box transcription factor TBX2; TBX2_HUMAN; TBX2. |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, (predicted: Rat, Dog, Cow, Rabbit, ) |
产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 74kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TBX2: 401-500/702 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. Function: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. Subunit: Interacts with PML (isoform-PML-2, isoform PML-3 and isoform PML-4). Subcellular Location: Nucleus (Potential). Tissue Specificity: Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. Similarity: Contains 1 T-box DNA-binding domain. |