规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 7 |
100ul | ¥ 1900 | 6 |
100ul | ¥ 2900 | 6 |
产品编号 | Ys-1683R |
英文名称 | CNR1 |
中文名称 | 钙粘蛋白相关的神经受体1抗体 |
别 名 | Cannabinoid Receptor I; CANN 6; CANN6; Cannabinoid receptor I brain; CB 1; CB R; CB1; CB1A; CB1K5; CbR; Central cannabinoid receptor; Central cannabinoid receptor isoform a; Central cannabinoid receptor isoform b; CNR 1; CNR; CNR-1; CNR1_HUMAN. |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 52kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CNR-1: 401-472/472 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] Function: Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. Subunit: Interacts (via C-terminus) with CNRIP1. Subcellular Location: Cell membrane. Tissue Specificity: Widely expressed. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P21554 Gene ID: 1268 |