规格 | 价格 | 库存 |
---|---|---|
50ul | ¥ 1200 | 9 |
100ul | ¥ 1900 | 7 |
200ul | ¥ 2900 | 6 |
产品编号 | ys-1200R |
英文名称 | Omgp |
中文名称 | 少突细胞髓磷脂糖蛋白抗体 |
别 名 | olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN. |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, (predicted: Cow, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 43kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Omgp: 166-280/440 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin. Function: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. Subunit: Binds to RTN4R. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Oligodendrocytes and myelin of the central nervous system. Post-translational modifications: O-glycosylated in its Ser/Thr-rich repeat domain (Potential). Similarity: Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. SWISS: P23515 Gene ID: 4974 OMgp也是髓鞘糖蛋白的一种,在发育期促进轴突生长,成熟期抑制轴突生长.其抑制作用主要由髓鞘来源的抑制分子的共同受体NgR介导,在神经营养因子受体p75NTR以及小GTP酶Rho等信号分子的共同参与下完成. |
产品图片 | ![]() Sample: Medulla (Mouse) Lysate at 30 ug Primary: Anti- Omgp (bs-1200R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 49 kD ![]() Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Rat Cerebellum tissue lysates Primary: Anti-Omgp (bs-1200R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kDa Observed band size: 48 kDa |