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淋巴细胞抗原75抗体
产品名称:
淋巴细胞抗原75抗体
英文名称:
Ly75/CD205
产品类别:
抗体
产品编号:
Ys-2565R
产品应用:
ELISA
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
1年
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50UL ¥ 1200 8
100ul ¥ 1900 6
200ul ¥ 2900 8

产品详情

 

产品编号 Ys-2565R
英文名称 Ly75/CD205
中文名称 淋巴细胞抗原75抗体
别    名 C-type lectin domain family 13 member B; CD 205; CD205; CD205 antigen; CLEC 13B; CLEC13B; DEC 205; DEC-205; DEC205; gp200; gp200 MR6; gp200-MR6; LY 75; Ly-75; LY75; LY75_HUMAN; Lymphocyte antigen 75; Renal Cell Carcinoma (gp200).  
研究领域 肿瘤  细胞类型标志物  b-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, )
产品应用 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 195kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEC-205: 601-700/1722 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Ly75 is expressed in spleen, thymus, colon and peripheral blood lymphocytes and causes reduced proliferation of B-lymphocytes as well as acting as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Ly75 is also detected in myeloid and B lymphoid cell lines and isoforms 2 and 3 are expressed in Hodgkin and Reed-Sternberg (HRS) cells (malignant Hodgkin lymphoma cells).

Function:
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

Post-translational modifications:
N-glycosylated.

Similarity:
Contains 10 C-type lectin domains.
Contains 1 fibronectin type-II domain.
Contains 1 ricin B-type lectin domain.

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