规格 | 价格 | 库存 |
---|---|---|
50UL | ¥ 1200 | 4 |
100UL | ¥ 1900 | 5 |
200UL | ¥ 2900 | 2 |
产品编号 | Ys-2453R |
英文名称 | CCL17 |
中文名称 | 胸腺活化调节趋化因子抗体 |
别 名 | TARC; CCL17; SCYA17; ABCD-2; C-C motif chemokine 17; A152E53; CC Chemokine TARC; CCL17; Chemokine CC Motif Ligand 17; MGC138271; MGC138273; Small Inducible Cytokine A17; Small Inducible Cytokine A17 Precursor; Small Inducible Cytokine Subfamily A (Cys Cys); Small Inducible Cytokine Subfamily A (Cys Cys) Member 17; T Cell Directed CC Chemokine; Thymus and activation regulated chemokine; CCL17_HUMAN. |
研究领域 | 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, (predicted: Mouse, Rat, ) |
产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 8kDa |
细胞定位 | 分泌型蛋白 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CCL17: 41-103/103 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 | Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. Function: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Subcellular Location: Secreted. Tissue Specificity: Expressed at high levels in thymus and at low levels in the lung, colon and small intestine. Post-translational modifications: One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. Similarity: Belongs to the intercrine beta (chemokine CC) family. SWISS: Q92583 Gene ID: 6361 |