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细胞球蛋白抗体
产品名称:
细胞球蛋白抗体
英文名称:
CYGB
产品类别:
抗体
产品编号:
Ys-0590R
产品应用:
ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
1年
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1200 6
100UL ¥ 1900 5
200UL ¥ 2900 5

产品详情

 

产品编号 Ys-0590R
英文名称 CYGB
中文名称 细胞球蛋白抗体
别    名 Cytoglobin; HGB; STAP; Histoglobin; HGb; cell activation-associated protein; CYGB_HUMAN.  

 

研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, Chicken, Dog, Cow, Horse, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 21kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human cytoglobin: 87-132/190 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]

Function:
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine.

Similarity:
Belongs to the globin family.

SWISS:
Q8WWM9

Gene ID:
114757




细胞球蛋白Cygb是最近发现的脊椎动物球蛋白超家族的一员,在体内分布广泛。 有学者认为:Cygb的确切功能尚不十分清楚,目前主要有携氧与储氧、氧感受器、活性氧基团和NO的清道夫、NADH氧化酶或过氧化氢酶样作用和参与胶原形成等假说。
产品图片

Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Cygb Polyclonal Antibody, Unconjugated(bs-0590R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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