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白介素22受体抗体
产品名称:
白介素22受体抗体
英文名称:
IL22R
产品类别:
抗体
产品编号:
Ys-2624R
产品应用:
WB ELISA
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
1年
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50UL ¥ 1100 6
100UL ¥ 1900 5
200UL ¥ 2900 2

产品详情

 

产品编号 Ys-2624R
英文名称 IL22R
中文名称 白介素22受体抗体
别    名 IL-22R; CRF2 9; IL22 Receptor Alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9.  

 

抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 61kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-22R: 41-150/574 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008].

Function:
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Subunit:
Heterodimer with IL10RB and with IL20RB.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in kidney, liver and lung.

Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.

SWISS:
Q8N6P7

Gene ID:
58985



 
产品图片
Sample:
Lane1: Liver(Mouse) Lysate at 30 ug
Lane2: Intestinal(Mouse) Lysate at 30 ug
Primary: Anti-IL22R (bs-2624R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size : 61kD
Observed band size : 61kD
Sample:
placenta (Mouse) Lysate at 40 ug
Primary: Anti-IL22R (Bs-2624R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 65 kD

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