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内皮脂肪酶抗体
产品名称:
内皮脂肪酶抗体
英文名称:
Endothelial lipase
产品类别:
抗体
产品编号:
Ys-2397R
产品应用:
WB ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
1年
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50UL ¥ 1100 7
100UL ¥ 1900 5
200UL ¥ 2900 3

产品详情

 


产品编号 Ys-2397R
英文名称 Endothelial lipase
中文名称 内皮脂肪酶抗体
别    名 LIPG; EC 3.1.1.3; EDL; EL; Endothelial cell-derived lipase; Endothelial lipase; Endothelial lipase precursor; Lipase endothelial; LIPE_HUMAN; LIPG; Lipoprotein lipase H; PL; PRO719.  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号 55kDa
交叉反应 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 55kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Endothelial lipase: 301-400/500 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008].

Function:
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.

Subunit:
Head to tail homodimer.

Subcellular Location:
Secreted.

Tissue Specificity:
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.

Similarity:
Belongs to the AB hydrolase superfamily. Lipase family.
Contains 1 PLAT domain.

SWISS:
Q9Y5X9

Gene ID:
9388

Database links:

 



EL被确定为甘油三酯脂肪酶家族的新成员,由于EL是由血管内皮细胞合成和分泌,因此被命名为内皮脂肪酶,相应的基因命名为内皮脂肪酶基因(endothelial lipase gene,LIPG)。EL也是一种分泌型蛋白,由483个氨基酸组成,分子量约55kD,在人体多种组织中都有表达:冠状动脉、胎盘、甲状腺、肝脏、肺脏、肾脏、睾丸和卵巢等组织中都可发现。
产品图片
Sample: Placenta (Mouse) Lysate at 40 ug
Primary: Anti- Endothelial lipase (bs-2397R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD

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