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KREMEN1蛋白抗体
产品名称:
KREMEN1蛋白抗体
英文名称:
KREMEN1
产品类别:
抗体
产品编号:
Ys-16812R
保质期:
一年
保存条件:
-20℃
[价格]
规格 价格 库存
50ul ¥ 1138 10
100ul ¥ 1880 10
200ul ¥ 2900 1

产品详情

 

英文名称 KREMEN1
中文名称 KREMEN1蛋白抗体
别    名 AV002070; Dickkopf receptor; KREM1_HUMAN; KREMEN; Kremen protein 1; Kremen protein 1 precursor; Kremen1; Kringle coding gene marking the eye and the nose; Kringle containing protein marking the eye and the nose; Kringle containing transmembrane protein 1; Kringle containing transmembrane protein; Kringle domain containing transmembrane protein 1; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose; KRM1; RP23 293J16.1.  
研究领域 细胞生物  信号转导  细胞膜受体 
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Cow, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KREMEN1:101-200/473 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
产品介绍 This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). {ECO:0000250}.

Subcellular Location:
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Similarity:
Contains 1 CUB domain.

SWISS:
Q96MU8

Gene ID:
83999

Database links:

Entrez Gene: 83999 Human

Omim: 609898 Human

SwissProt: Q96MU8 Human

Unigene: 229335 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

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