产品分类/PRODUCT CLASSIFICATION
| 英文名称 | CHRNA1(97-116) Peptide |
| 中文名称 | 乙酰胆碱受体前体蛋白AChRα1多肽 |
| 别 名 | Nicotinic Acetylcholine Receptor alpha 1; Acetylcholine receptor protein alpha chain Precursor; Acetylcholine receptor subunit alpha; ACHA_HUMAN; ACHRA; CHNRA; Cholinergic receptor nicotinic alpha polypeptide 1; Cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle); CHRNA1; Nicotinic cholinergic receptor alpha 1; Schizophrenia neurophysiologic defect candidate. |
| 性 状 | Lyophilized powder |
| 序 列 | FSHLQNEQWVDYNLKWNPDD |
| 产品来源 | 合成 |
| 纯化方法 | HPLC |
| 产品应用 | Biological activity |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 产品介绍 | Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR?, also known as ACHRD, CHRNA, CMS2A, FCCMS, SCCMS or CHRNA1, is a 482 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms, which are expressed in different tissues. Isoform 1 is only expressed in skeletal muscle whereas isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus. Sequence: FSHLQNEQWVDYNLKWNPDD Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 乙酰胆碱受体α亚基97-116肽段，用于制作实验性重症肌无力模型的研究。 |
