中文名称 转录因子SOX-11蛋白重组兔单克隆抗体
别 名 SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.
研究领域 肿瘤 细胞生物 神经生物学 信号转导 干细胞 转录调节因子 表观遗传学
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 1E8
交叉反应 (predicted: Human, )
产品应用 WB=1:500-1000 IP=1:20-100 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞核
性 状 Liquid
浓 度 1mg/ml
免 疫 原 Recombinant human SOX11 protein (1-100aa):
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
Function:
Transcriptional activator.
Subcellular Location:
Nucleus.
Tissue Specificity:
Mainly expressed in the developing central nervous system.
Similarity:
Contains 1 HMG box DNA-binding domain.
SWISS:
P35716
Gene ID:
6664
Database links:
Entrez Gene: 6664 HumanEntrez Gene: 20666 MouseEntrez Gene: 84046 RatOmim: 600898 HumanSwissProt: P35716 HumanSwissProt: Q7M6Y2 MouseSwissProt: P0C1G9 RatUnigene: 432638 HumanUnigene: 41702 MouseUnigene: 466344 MouseUnigene: 162854 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
