中文名称 重组兔脂肪酸合成酶单克隆抗体
别 名 fatty acid synthase;FAS; FASN; FA Synthase 1; MGC14367; MGC15706; OA-519; Fatty acid synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Enoyl-[acyl-carrier-protein] reductase; Oleoyl-[acyl-carrier-protein] hydrolase; FAS_HUMAN.
研究领域 肿瘤 心血管 免疫学 神经生物学 信号转导 激酶和磷酸酶 合成与降解
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 9B6
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 WB=1:1000 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:50-200 IHC-F=1:450-200 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 273kDa
细胞定位 细胞浆
性 状 Liquid
浓 度 1mg/ml
免 疫 原 Recombinant human Fatty Acid Synthase:
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation.
Function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Subunit:
Homodimer which is arranged in a head to tail fashion.
Subcellular Location:
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity:
Ubiquitous. Prominent expre
