英文名称 Dopamine Receptor D1
中文名称 多巴胺受体D1重组兔单克隆抗体
别 名 DRD1; dopamine D1 receptor; D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine Receptor D1; DR D1; DR D1A; DRD 1; DRD1 receptor; DRD1; DRD1A; DRD1_HUMAN; D(1A) dopamine receptor; DRD 1A; DRD1.
研究领域 肿瘤 免疫学 神经生物学
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 3C3
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞浆 细胞膜
性 状 Liquid
浓 度 1mg/ml
免 疫 原 C-terminus human Dopamine Receptor D1:
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Function:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Subunit:
Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Detected in caudate, nucleus accumbens and in the olfactory tubercle.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
P21728
Gene ID:
1812
Database links:
Entrez Gene: 1812 HumanEntrez Gene: 13488 MouseEntrez Gene: 24316 RatOmim: 126449 HumanSwissProt
