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神经丝蛋白抗体
产品名称:
神经丝蛋白抗体
英文名称:
Neuronal thread protein AD7c-NTP
产品类别:
抗体
产品编号:
0046
产品应用:
WB ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
50ul ¥ 1280 1
100ul ¥ 1980 1
200ul ¥ 2980 2

产品详情

 

中文名称 神经丝蛋白抗体
别    名 neuronal thread protein AD7c-NTP; AD7c-NTP.  

 

研究领域 神经生物学  信号转导  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, )
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuronal thread protein AD7c-NTP:301-375/375 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease.

SWISS:
N/A

Gene ID:
N/A

Database links:

GenBank: AAC08737



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

AD7C-NTP是存在于神经元中的一种41Kda的蛋白质,在AD患者脑内选择性升高,和其病理过程相关,AD7C-NTP基因也只在神经元表达,AD患者脑脊液中AD7C-NTP表达升高, AD7C-NTP作为AD早期诊断和确诊的生物化学标志正引起越来越多的关注.
产品图片 Sample: Brain (Mouse) Lysate at 40 ug
Primary: Anti- AD7c-NTP(bs-0046R) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 41 kD
Observed band size: 41 kD
Tissue/cell: Mouse brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-AD7c-NTP Polyclonal Antibody, Unconjugated(bs-0046R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: human brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-AD7c-NTP Polyclonal Antibody, Unconjugated(bs-0046R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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