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磷酸化离子通道蛋白Kv3.1抗体
产品名称:
磷酸化离子通道蛋白Kv3.1抗体
英文名称:
phospho-KCNC1 (Ser503)
产品类别:
抗体
产品编号:
5403
产品应用:
WB ELISA IHC-P IHC-F IF
性状:
Liquid
纯化方法:
affinity purified by Protein A
保质期:
1年
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
100ul ¥ 1980 200

产品详情

 

中文名称 磷酸化离子通道蛋白Kv3.1抗体
别    名 KCNC1 (phospho S503); p-KCNC1 (phospho Ser503); C230009H10Rik; FLJ41162; FLJ42249; FLJ43491; Kcr2 1; KShIIIB; Kv3.1; Kv4; MGC129855; NGK2; Potassium voltage-gated channel subfamily C member 1; Shaw; Voltage gated potassium channel; KCNC1_RAT; Voltage gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv3.1; KCNC1_RAT.  
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  神经生物学  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat KCNC1 around the phosphorylation site of Ser503:AD(p-S)KL 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.

Function:
This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Subunit:
Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

SWISS:
P25122

Gene ID:
25327

Database links:

Entrez Gene: 3746 Human

Entrez Gene: 16502 Mouse

Entrez Gene: 25327 Rat

Omim: 176258 Human

SwissProt: P48547 Human

SwissProt: P15388 Mouse

SwissProt: P25122 Rat

Unigene: 303870 Human

Unigene: 552896 Human

Unigene: 249386 Mouse

Unigene: 33095 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 
产品图片 Sample:
HL60(Human) Cell Lysate at 30 ug
Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD
Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD
Sample:
U2OS(Human) Cell Lysate at 30 ug
Hela (Human) Cell Lysate at 30 ug
Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD
Sample:
HL60(Human) Cell Lysate at 30 ug
> Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD

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