雄激素受体（AR）抗体-上海雅吉生物科技有限公司

规格	价格	库存
50ul	￥ 1280	1
100ul	￥ 1980	1
200ul	￥ 2980	1

英文名称

AR/Androgen Receptor Rabbit pAb

中文名称

雄激素受体（AR）抗体

英文别名

Androgen receptor isoform 2; AIS; AIS; ANDR_HUMAN; Androgen receptor(dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); Androgen receptor; AR; DHTR; Dihydro Testosterone Receptor; Dihydrotestosterone receptor; HUMARA; HYSP1; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; Spinal and bulbar muscular atrophy; TFM; AR.

产品应用

应用	已检合格种属	预测种属	推荐稀释比例
WB	Human, Mouse	Rat	1:500-2000
IHC-P	Human, Mouse, Rat		1:50-200
IHC-F	Human, Mouse, Rat		1:50-200
IF	Human, Mouse, Rat		1:50-200

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

交叉反应

Human, Mouse, Rat

抗体来源

Rabbit

免疫原

KLH conjugated synthetic peptide derived from human Androgen receptor isoform 2 : 825-919/919

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Polyclonal

理论分子量

43/101 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

SWISS

P10275

Gene ID

367

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 367 Human

Entrez Gene : 11835 Mouse

Entrez Gene : 24208 Rat

Omim : 313700 Human

SwissProt : P10275 Human

SwissProt : P19091 Mouse

SwissProt : P15207 Rat

Unigene : 496240 Human

Unigene : 39005 Mouse

Unigene : 394224 Mouse

Unigene : 439657 Mouse

Unigene : 9813 Rat

Entrez Gene : 367 Human

Entrez Gene : 11835 Mouse

Entrez Gene : 24208 Rat

UniProtKB : P10275 Human

UniProtKB : P19091 Mouse

UniProtKB : P15207 Rat

背景资料

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

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