产品分类/PRODUCT CLASSIFICATION
| 中文名称 | 干扰素β抗体 |
| 别 名 | Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFNB 1; IFNB; IFNB1; Interferon beta 1 fibroblast; Interferon beta precursor; MGC96956. |
| 研究领域 | 肿瘤 细胞生物 免疫学 干扰素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IFN-Beta:101-187/187 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction. Function: Has antiviral, antibacterial and anticancer activities. Subunit: Monomer. Subcellular Location: Secreted. Similarity: Belongs to the alpha/beta interferon family. SWISS: P01574 Gene ID: 3456 Database links: Entrez Gene: 3456 Human Omim: 147640 Human SwissProt: P01574 Human Unigene: 93177 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. β型干扰素(Interferon-β,IFN-β)是主要由成纤维细胞产生的细胞因子,属于单一基因编码产生的蛋白质,可通过干扰病毒RNA或DNA复制而抑制病毒生长,并可显著增强NK细胞杀伤活性,通过促进MHCⅠ类分子表达而增强CTL对病毒感染细胞的识别和杀伤作用. |
| 产品图片 |  Paraformaldehyde-fixed, paraffin embedded (human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Tissue/cell: human colon cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IFN-Beta/Ifnb1 Polyclonal Antibody, Unconjugated(bs-0787R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining  Tissue/cell: human colon cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IFN-Beta/Ifnb1 Polyclonal Antibody, Unconjugated(bs-0787R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining  Paraformaldehyde-fixed, paraffin embedded (human endometrial carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. |
