文章标题：Genetic polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) and risk of vitiligo in Han Chinese populations: a genotype–phenotype correlation study
作者列表：Chen J.‐X., Shi Q., Wang X.‐W., Guo S., Dai W., Li K., Song P., Wei C., Wang G., Li C.‐Y., Gao T.‐W.
影响因子：4.1
期刊：BRITISH JOURNAL OF DERMATOLOGY
发表时间：2014-5-1
DOI:10.1111/bjd.12845
文献主题：
Summary
Background
Recent evidence has revealed an elevation of total homocysteine (tHcy) in patients with vitiligo. Methylenetetrahydrofolate reductase (MTHFR) is one of the main enzymes regulating homocysteine (Hcy) metabolism. Thus, polymorphisms of MTHFR could potentially contribute to the development of vitiligo by affecting MTHFR activity and tHcy levels.
Objectives
To evaluate the potential association between MTHFR polymorphisms and vitiligo susceptibility.
